Tamoxifen Adverse Effect: increased risk of hemolytic uremic syndromeClinical Management: Monitor patients for signs of hemolytic uremic syndrome. 
 Vinblastine Adverse Effect: pulmonary toxicity (pulmonary edema)Clinical Management: The potential hazards of administering these two drugs together should be realized. Patients should be monitored for severe and life-threatening bronchospasm. 
Vinorelbine Adverse Effect: Acute pulmonary reactionsClinical Management: Avoid the concurrent use of Vinorelbine and Mitomycin if possible. 
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